Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854269 | 0.93 | RAB9A (0.46) | RAB9ANPC1MAPTP2RX7GAA | |
| SCHEMBL2850258 | 0.92 | MAPT (0.51) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2854221 | 0.90 | MAPT (0.51) | MAPTMEN1KMT2AP2RX7GAA | |
| SCHEMBL2852565 | 0.90 | MAPT (0.42) | RAB9ANPC1MAPTCYP1A2CYP3A4 | |
| SCHEMBL2853385 | 0.89 | MAPT (0.42) | MAPTCYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL2848615 | 0.89 | MAPT (0.44) | NPC1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2853258 | 0.89 | NPY5R (0.45) | RAB9ANPC1MAPTCYP3A4MEN1 | |
| SCHEMBL2852360 | 0.89 | MAPT (0.42) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2848317 | 0.89 | MAPT (0.46) | NPC1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2860939 | 0.88 | LMNA (0.45) | RAB9ANPC1MAPTCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |