SCHEMBL2859375

SCHEMBL2859375

C=CC(C)CC/C(C)=C/COCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LSS P48449 2/20 0.39
TRPV1 Q8NER1 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.36
FAAH O00519 2/20 0.35
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 1/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
KMT2A Q03164 1/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2859377 1.00 LSS (0.39) LSSTRPV1TSHRHTTFAAH
SCHEMBL11293116 0.81 NDUFS8 (0.45) LSSTRPV1TSHRHTTCA1
SCHEMBL11293118 0.81 NDUFS8 (0.45) LSSTRPV1TSHRHTTCA1
SCHEMBL2863861 0.81 NDUFS8 (0.39) TRPV1ALDH1A1KMT2A
SCHEMBL2867599 0.78 FAAH (0.40) TSHRHTTFAAHALDH1A1CA1
SCHEMBL2867602 0.78 FAAH (0.40) TSHRHTTFAAHALDH1A1CA1
SCHEMBL9508252 0.76 TSHR (0.47) LSSTRPV1TSHRHTTALOX5
SCHEMBL9508258 0.76 TSHR (0.47) LSSTRPV1TSHRHTTALOX5
SCHEMBL2866740 0.76 PTPN1 (0.33) LSS
SCHEMBL2866741 0.76 PTPN1 (0.33) LSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7728180-B2 Method for producing ethers KURARAY CO., LTD. (JP) 2010-06-01 US disclosed
US-20080262272-A1 Method For Producing Ethers KURARAY CO., LTD. (JP) 2008-10-23 US disclosed
CN-1972888-A Method for producing ethers KURARAY CO (JP) 2007-05-30 CN disclosed
EP-1760061-A1 METHOD FOR PRODUCING ETHERS KURARAY CO., LTD. (JP) 2007-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080262272-A1 Method For Producing Ethers TELO2, PDS5A, TERT LSS 1302/4885TRPV1 4274/4885TSHR 657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.