Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 19/20 | 0.53 |
| ▸ | LIPC | P11150 | 7/20 | 0.53 |
| ▸ | LPL | P06858 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28593878 | 1.00 | LIPG (0.53) | LIPGLIPCLPLCYP1A2CYP3A4 | |
| SCHEMBL28601509 | 0.88 | LIPG (0.52) | LIPGLIPCLPLMAPTCYP2C9 | |
| SCHEMBL28601507 | 0.88 | LIPG (0.52) | LIPGLIPCLPLMAPTCYP2C9 | |
| SCHEMBL28603230 | 0.83 | LIPG (0.49) | LIPGLIPCLPL | |
| SCHEMBL12210088 | 0.81 | LIPG (0.61) | LIPGLIPCLPL | |
| SCHEMBL28601649 | 0.81 | LMNA (0.46) | LIPGLIPCLPLCYP1A2CYP3A4 | |
| SCHEMBL28601654 | 0.81 | LMNA (0.46) | LIPGLIPCLPLCYP1A2CYP3A4 | |
| SCHEMBL21624697 | 0.81 | NOTUM (0.59) | LIPGLIPCLPL | |
| SCHEMBL21624699 | 0.81 | NOTUM (0.59) | LIPGLIPCLPL | |
| SCHEMBL28180872 | 0.81 | ACACB (0.41) | LIPGLIPCLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164461-A | Heterocyclic derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2021-07-23 | — | — | CN | disclosed |