Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 14/20 | 0.45 |
| ▸ | LPL | P06858 | 2/20 | 0.45 |
| ▸ | LIPC | P11150 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601649 | 1.00 | LMNA (0.46) | LMNALIPGLPLLIPCGPR119 | |
| SCHEMBL28601509 | 0.93 | LIPG (0.52) | LIPGLPLLIPCGPR119CYP2C9 | |
| SCHEMBL28601507 | 0.93 | LIPG (0.52) | LIPGLPLLIPCGPR119CYP2C9 | |
| SCHEMBL28605634 | 0.84 | FFAR4 (0.44) | LIPGLPL | |
| SCHEMBL28605632 | 0.84 | FFAR4 (0.44) | LIPGLPL | |
| SCHEMBL28605702 | 0.84 | GPR119 (0.45) | LMNALIPGLPLLIPCGPR119 | |
| SCHEMBL28607789 | 0.82 | SMN1; SMN2 (0.55) | LMNACYP2C9CYP2C19MAPTKDM4E | |
| SCHEMBL28603224 | 0.82 | SMN1; SMN2 (0.55) | LMNACYP2C9CYP2C19MAPTKDM4E | |
| SCHEMBL21626176 | 0.82 | NOTUM (0.53) | HPGDGAA | |
| SCHEMBL21626177 | 0.82 | NOTUM (0.53) | HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164461-A | Heterocyclic derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2021-07-23 | — | — | CN | disclosed |