Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940910 | 0.79 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15142128 | 0.79 | GCK (0.39) | GCKALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL28816899 | 0.79 | KMT2A (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2SIRT2 | |
| SCHEMBL28286226 | 0.78 | DYRK1A (0.43) | MEN1KMT2AGCKALDH1A1HPGD | |
| SCHEMBL28940975 | 0.75 | MEN1 (0.37) | MEN1KMT2AHPGDSMN1; SMN2PARP1 | |
| SCHEMBL24655830 | 0.75 | MAP4K1 (0.40) | MEN1KMT2AGCKALDH1A1HPGD | |
| SCHEMBL459076 | 0.75 | KMT2A (0.43) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29225084 | 0.75 | SIRT2 (0.43) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28595145 | 0.74 | ALDH1A1 (0.39) | MEN1KMT2AGCKALDH1A1HPGD | |
| SCHEMBL15780518 | 0.72 | APLNR (0.41) | MEN1KMT2AGCKALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |