SCHEMBL2859525

SCHEMBL2859525

Cc1ccccc1C(C)c1ccc(O)cc1O

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.64
MGAM O43451 2/20 0.40
GAA P10253 2/20 0.40
SI P14410 2/20 0.40
MGAM2 Q2M2H8 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
TRPA1 O75762 1/20 0.40
LMNA P02545 1/20 0.40
CHRM1 P11229 1/20 0.40
SLC6A2 P23975 1/20 0.40
ADRA1A P35348 1/20 0.40
HTR2B P41595 1/20 0.40
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492423 1.00 TYR (0.64) TYRMGAMGAASIMGAM2
SCHEMBL12324037 0.87 TYR (0.59) TYRMGAMGAASIMGAM2
SCHEMBL13532442 0.87 TYR (0.70) TYRMGAMGAASIMGAM2
SCHEMBL2860364 0.86 TYR (0.46) TYRCYP1A2CYP2C19LMNAGABRA1
SCHEMBL51618 0.84 TYR (0.70) TYRTRPA1LMNACHRM1SLC6A2
SCHEMBL6251589 0.83 GABRA1 (0.58) TYRGAACYP1A2TRPA1LMNA
SCHEMBL23922718 0.79 TYR (0.60) TYRMGAMGAASIMGAM2
SCHEMBL29492399 0.79 TYR (0.60) TYRMGAMGAASIMGAM2
SCHEMBL9763719 0.78 ESR2 (0.47) TYRTRPA1LMNACHRM1SLC6A2
SCHEMBL146510 0.78 ESR1 (0.56) GAACYP1A2CYP2C19SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4142680-B1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B V (NL) 2023-10-18 EP disclosed
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2023-09-19 US disclosed
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-15 US disclosed
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-01 US disclosed
EP-4142680-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE Unilever IP Holdings B.V. (NL) 2023-03-08 EP disclosed
US-11596586-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2023-03-07 US disclosed
US-20220211596-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2022-07-07 US disclosed
US-11260005-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2022-03-01 US disclosed
WO-2021219378-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B.V. (NL) 2021-11-04 WO disclosed
EP-3558246-B1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS UNILEVER IP HOLDINGS B V (NL) 2021-10-20 EP disclosed
US-20200108000-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2020-04-09 US disclosed
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
CN-100364160-C Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES (JP) 2008-01-23 CN disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11596586-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885MGAM 3531/4885GAA 2139/4885
US-11260005-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885MGAM 3531/4885GAA 2139/4885
US-20220211596-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885MGAM 3531/4885GAA 2139/4885
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE NAA40, CRAT, NQO1 TYR 139/4885MGAM 3819/4885GAA 1504/4885
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885MGAM 3531/4885GAA 2139/4885
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885MGAM 3531/4885GAA 2139/4885
US-20200108000-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885MGAM 3531/4885GAA 2139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.