SCHEMBL28595282

SCHEMBL28595282

CC(O)C(O)Oc1cccc(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
OGG1 O15527 1/20 0.55
GRM5 P41594 1/20 0.48
KMT2A Q03164 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
SLC6A4 P31645 1/20 0.43
KDM4E B2RXH2 2/20 0.42
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
WDR5 P61964 1/20 0.41
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30267527 1.00 OGG1 (0.55) OGG1GRM5KMT2AL3MBTL1ALDH1A1
SCHEMBL10359842 0.85 OGG1 (0.58) OGG1GRM5KMT2AL3MBTL1ALDH1A1
SCHEMBL105734 0.80 OGG1 (0.57) OGG1GRM5KMT2AL3MBTL1ALDH1A1
SCHEMBL2557633 0.79 LMNA (0.52) KMT2AALDH1A1MAPT
SCHEMBL31514931 0.79 LMNA (0.52) KMT2AALDH1A1MAPT
Chloromethane SCHEMBL27541396 0.79 OGG1 (0.56) OGG1GRM5KMT2AL3MBTL1ALDH1A1
SCHEMBL10451483 0.79 OGG1 (0.56) OGG1GRM5KMT2AL3MBTL1ALDH1A1
SCHEMBL7154353 0.78 HPGD (0.50) KMT2AL3MBTL1SLC6A4HPGD
SCHEMBL17032600 0.77 OGG1 (0.54) OGG1GRM5KMT2AL3MBTL1ALDH1A1
SCHEMBL8059974 0.77 OGG1 (0.58) OGG1GRM5KMT2AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117838927-A Preparation method of mechanical reinforced calcium phosphate bone cement for promoting bone plexus structure 西安理工大学 2024-04-09 CN disclosed
CN-115942976-A Masked IL-2 cytokines and cleavage products thereof 西里欧发展公司 2023-04-07 CN disclosed
CN-115867568-A Masked IL-15 cytokines and cleavage products thereof 西里欧发展公司 2023-03-28 CN disclosed
CN-115734806-A Masked IL-12 cytokines and cleavage products thereof 西里欧发展公司 2023-03-03 CN disclosed
CN-104136041-B Targeted chondroitin sulfate glycans VAR2制药有限公司 2021-06-29 CN disclosed