SCHEMBL2859537

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2867251	0.88	FGFR1 (0.54)	FGFR1KDM4ESMN1; SMN2MAP2K4MAPK1
	SCHEMBL13198204	0.81	FLT3 (0.54)	FGFR1KDM4EMAPK1ILKMAPK3
	SCHEMBL2860415	0.81	MAPK10 (0.54)	ITKMAP2K4MAPK1MAPKAPK3MAPK6
	SCHEMBL2867170	0.79	ITK (0.52)	ITKMAP2K4MAPK1MAPKAPK3MAPK6
	SCHEMBL2866791	0.79	MAP2K4 (0.69)	KDM4ESMN1; SMN2ITKMAP2K4MAPK1
	SCHEMBL1224535	0.77	FLT3 (0.66)	FGFR1KDM4ESMN1; SMN2ITKKMT2A
	SCHEMBL2867324	0.76	PIM1 (0.56)	ITKMAP2K4MAPK1MAPKAPK3MAPK6
	SCHEMBL2867287	0.76	MAP2K4 (0.51)	ITKMAP2K4MAPK1MAPKAPK3MAPK6
	SCHEMBL2861172	0.76	LRRK2 (0.61)	KDM4EITKMAP2K4MAPK1MAPKAPK3
	SCHEMBL2855850	0.74	MAP2K4 (0.59)	ITKMAP2K4MAPK1MAPKAPK3MAPK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.