SCHEMBL2867251

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2859537	0.88	FGFR1 (0.53)	FGFR1ILKMAPTRAB9ANPC1
	SCHEMBL5377524	0.81	MAPK10 (0.53)	FGFR1MAP2K4KDM4EFLT1MAPK1
	SCHEMBL2866668	0.80	ALOX15 (0.44)	FGFR1ALDH1A1RAB9ANPC1MAP2K4
	SCHEMBL13198204	0.78	FLT3 (0.54)	FGFR1ILKALDH1A1KDM4EMAPK1
	SCHEMBL2863569	0.77	LRRK2 (0.56)	MAP2K4KDM4EMAPK1FLT3
	SCHEMBL2860104	0.77	PIM1 (0.53)	FGFR1ALDH1A1RAB9ANPC1MAP2K4
	SCHEMBL5379661	0.77	MAPK1 (0.46)	MAPTRAB9ANPC1MAP2K4KDM4E
	SCHEMBL2861069	0.76	ALPL (0.54)	MEN1KMT2AMAP2K4KDM4EMAPK1
	SCHEMBL2857271	0.76	MAPK1 (0.46)	FGFR1MAP2K4KDM4EFLT1MAPK1
	SCHEMBL16405025	0.75	ALDH1A1 (0.60)	ALDH1A1MAPTRAB9ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.