SCHEMBL2867170

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2866668	0.86	ALOX15 (0.44)	ITKMAPK1MAP2K4NPC1RAB9A
	SCHEMBL2855850	0.81	MAP2K4 (0.59)	ITKMAPK1MAP2K4MAPKAPK3MAPK6
	SCHEMBL2868673	0.80	CHEK1 (0.44)	CHEK1
	SCHEMBL13198202	0.80	CHEK1 (0.44)	CHEK1
	SCHEMBL2866791	0.80	MAP2K4 (0.69)	ITKMAPK1MAP2K4MAPKAPK3MAPK6
	SCHEMBL2861172	0.79	LRRK2 (0.61)	ITKMAPK1MAP2K4MAPKAPK3MAPK6
	SCHEMBL2859537	0.79	FGFR1 (0.53)	ITKMAPK1MAP2K4MAPKAPK3MAPK6
	SCHEMBL2867324	0.79	PIM1 (0.56)	ITKMAPK1MAP2K4MAPKAPK3MAPK6
	SCHEMBL2870415	0.79	CHEK1 (0.45)	MAPK1FLT3CHEK1
	SCHEMBL29363709	0.78	FGFR1 (0.55)	ITKMAP2K4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.