SCHEMBL2867324

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5373231	0.89	PIM1 (0.58)	PIM1PIM3PIM2MAP2K4MAPK1
	SCHEMBL2860104	0.86	PIM1 (0.53)	PIM1PIM3PIM2MAP2K4MAPK1
	SCHEMBL2855850	0.82	MAP2K4 (0.59)	MAP2K4MAPK1MAPK6MAPKAPK3ITK
	SCHEMBL2866791	0.81	MAP2K4 (0.69)	MAP2K4MAPK1MAPK6MAPKAPK3ITK
	SCHEMBL17179205	0.80	PIM1 (0.60)	PIM1PIM3PIM2ITKLRRK2
	SCHEMBL2867170	0.79	ITK (0.52)	MGAMMAP2K4MAPK1MAPK6MAPKAPK3
	SCHEMBL2864493	0.78	DYRK1A (0.46)	DYRK1A
	SCHEMBL13198203	0.78	DYRK1A (0.46)	DYRK1A
	SCHEMBL5377743	0.77	PIM1 (0.61)	PIM1PIM3PIM2LRRK2DYRK1A
	SCHEMBL2864569	0.77	MAP2K4 (0.52)	MAP2K4MAPK1MAPK6MAPKAPK3ITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.