SCHEMBL28595448

SCHEMBL28595448

Fc1ccc(N2c3ccccc3Sc3ccccc32)cc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.54
MAOA P21397 1/20 0.47
BCHE P06276 4/20 0.42
MGLL Q99685 1/20 0.41
NOX1 Q9Y5S8 3/20 0.40
ACHE P22303 2/20 0.40
THRB P10828 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
KDM1A O60341 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12190901 0.89 HDAC6 (0.62) HDAC6MAOABCHENOX1ACHE
SCHEMBL29851224 0.89 HDAC6 (0.62) HDAC6MAOABCHENOX1ACHE
SCHEMBL15470447 0.83 HDAC6 (0.57) HDAC6MAOABCHEMGLLNOX1
SCHEMBL29387100 0.83 HDAC6 (0.56) HDAC6MAOABCHENOX1ACHE
SCHEMBL342426 0.83 HDAC6 (0.56) HDAC6MAOABCHENOX1ACHE
SCHEMBL2497519 0.82 MAOA (0.45) HDAC6MAOABCHENOX1ACHE
SCHEMBL31563662 0.80 GAA (0.43) HDAC6MEN1KMT2A
SCHEMBL19151907 0.80 HDAC6 (0.54) HDAC6MAOABCHENOX1ACHE
SCHEMBL8183708 0.80 HDAC6 (0.54) HDAC6MAOABCHEMGLLNOX1
SCHEMBL21915333 0.80 HDAC6 (0.58) HDAC6MAOABCHENOX1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478460-B Organic luminescent material and preparation method thereof 华东理工大学 2024-09-10 CN disclosed
CN-113026036-B Method for synthesizing sulfur ylide compounds by using continuous flow electrochemical oxidation 南京工业大学 2022-06-07 CN disclosed
CN-114478460-A Organic luminescent material and preparation method thereof 华东理工大学 2022-05-13 CN disclosed
CN-113026036-A Method for synthesizing sulfur ylide compounds by using continuous flow electrochemical oxidation 南京工业大学 2021-06-25 CN disclosed