Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 8/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | BCL6 | P41182 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | ULK1 | O75385 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18188282 | 0.77 | PTK2B (0.59) | PTK2BKIF11BCL6PTK2SYK | |
| SCHEMBL18188109 | 0.74 | PTK2B (0.56) | PTK2BKIF11BCL6PTK2ULK1 | |
| SCHEMBL18188476 | 0.67 | KMT2A (0.43) | ULK1 | |
| SCHEMBL7138709 | 0.66 | KIF11 (0.80) | PTK2BKIF11BCL6PTK2 | |
| SCHEMBL21489762 | 0.63 | SMYD3 (1.00) | SMYD3ULK1 | |
| SCHEMBL19710217 | 0.63 | SMYD3 (1.00) | SMYD3ULK1 | |
| SCHEMBL18188230 | 0.63 | NPC1 (0.43) | ULK1 | |
| SCHEMBL16208518 | 0.63 | KIF11 (1.00) | PTK2BKIF11 | |
| SCHEMBL17544761 | 0.62 | ULK1 (0.69) | PTK2BPTK2ULK1 | |
| SCHEMBL3154998 | 0.62 | PTK2B (0.78) | PTK2BBCL6PTK2ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107835814-B | Azabenzimidazoles and their use as AMPA receptor modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | disclosed |