Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | NOS2 | P35228 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28265684 | 0.84 | PDE10A (0.54) | PDE10ACCR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28887389 | 0.84 | PDE10A (0.54) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9501972 | 0.84 | PDE10A (0.54) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22119735 | 0.78 | PDE10A (0.59) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28594352 | 0.77 | PDE10A (0.47) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL13959105 | 0.77 | PDE10A (0.50) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4819932 | 0.76 | ALDH1A1 (0.60) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL8544282 | 0.75 | CCR1 (0.50) | CCR1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL230859 | 0.75 | RELA (0.59) | PDE10ACCR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1031078 | 0.75 | PDE10A (0.59) | PDE10AMEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121502-A | Heteroaromatic hydrocarbon compound, intermediate, composition and application | 山东铂源生物医药有限公司 | 2021-07-16 | — | — | CN | disclosed |