Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 6/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396650 | 0.86 | MAPT (0.68) | ALDH1A1MAPTL3MBTL1CTSBMEN1 | |
| SCHEMBL8548121 | 0.76 | CTSB (0.60) | CCR1ALDH1A1MAPTL3MBTL1CTSB | |
| SCHEMBL8674834 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1CTSBHPRT1 | |
| SCHEMBL28596104 | 0.75 | PDE10A (0.54) | CCR1ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL8545888 | 0.74 | GRIA1 (0.38) | ALDH1A1MAPTL3MBTL1CTSBKDM4E | |
| SCHEMBL17011283 | 0.74 | CCR1 (0.52) | CCR1ALDH1A1MAPTL3MBTL1CTSB | |
| SCHEMBL8673214 | 0.73 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1CTSBHPRT1 | |
| SCHEMBL4819932 | 0.71 | ALDH1A1 (0.60) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL1258482 | 0.70 | CCR1 (1.00) | CCR1MAPTKDM4ECYP2D6HIF1A | |
| SCHEMBL1187593 | 0.69 | TSHR (0.40) | CCR1ALDH1A1MAPTL3MBTL1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624097-B1 | TARGETING RADIOACTIVE IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1998-03-18 | — | — | EP | disclosed |
| US-5707603-A | Pyridine complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions | NYCOMED IMAGING AS (NO) | 1998-01-13 | — | — | US | disclosed |
| US-5677445-A | DIAGNOSIS, THERAPY | NYCOMED IMAGING AS (NO) | 1997-10-14 | — | — | US | disclosed |
| US-5523402-A | COMPLEXING AGENTS FOR TARGETING RADIOACTIVE IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0639083-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1995-02-22 | — | — | EP | disclosed |
| US-5367080-A | PYRIDINE DERIVATIVES | STERLING WINTHROP INC. (US) | 1994-11-22 | — | — | US | disclosed |
| EP-0624097-A1 | TARGETING RADIOACTIVE IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1994-11-17 | — | — | EP | disclosed |
| US-5262526-A | Fluorescent compound, complex, reagent, and specific binding assay employing said reagent | DOJINDO LABORATORIES (JP) | 1993-11-16 | — | — | US | disclosed |
| WO-1993021957-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1993-11-11 | — | — | WO | disclosed |
| EP-0493745-A1 | Fluorescent compound, complex, reagent, and specific binding assay employing said reagent | DOJINDO LABORATORIES (JP) | 1992-07-08 | — | — | EP | disclosed |
| WO-1992008494-A2 | TARGETING RADIOACTIVE IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1992-05-29 | — | — | WO | disclosed |