Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501303 | 1.00 | TUBB1 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28415491 | 0.89 | KDM4E (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28596233 | 0.88 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TDP1MAPTTSHR | |
| SCHEMBL1321669 | 0.84 | MAPT (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29501305 | 0.84 | L3MBTL1 (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL348929 | 0.84 | L3MBTL1 (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL339501 | 0.84 | TUBB1 (0.45) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10741154 | 0.83 | MAPT (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL6904034 | 0.76 | KDM4E (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Ether SCHEMBL10749243 | 0.76 | MAPT (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121427-B | Quinoline derivative and preparation method and application thereof | 广东工业大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-113121427-A | Quinoline derivative and preparation method and application thereof | 广东工业大学 | 2021-07-16 | — | — | CN | disclosed |