Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839006 | 0.87 | MAOB (0.46) | HTR2ASMN1; SMN2IDO1MAOAMAOB | |
| SCHEMBL6030733 | 0.84 | CA1 (0.44) | TSHRCYP2A6HTR2ASMN1; SMN2TAAR1 | |
| SCHEMBL8290989 | 0.82 | TAAR1 (0.40) | CYP2A6HTR2ASMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL8456049 | 0.81 | ALDH1A1 (0.42) | CYP2A6HTR2ASMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL1922889 | 0.81 | TSHR (0.50) | TSHRSMN1; SMN2IDO1AGXTALDH1A1 | |
| SCHEMBL969878 | 0.79 | TSHR (0.46) | TSHRSMN1; SMN2LOXL2IDO1MAOA | |
| SCHEMBL28603322 | 0.79 | ABCB1 (0.52) | SMN1; SMN2TAAR1HTR1ADRD2 | |
| SCHEMBL1631357 | 0.78 | TSHR (0.44) | TSHRSMN1; SMN2IDO1MAOAMAOB | |
| SCHEMBL8397899 | 0.78 | ALDH1A1 (0.39) | CYP2A6HTR2ASMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL8835472 | 0.78 | CMA1 (0.42) | CYP2A6HTR2ASMN1; SMN2TAAR1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166182-A | Aminopeptidase A inhibitor and pharmaceutical composition comprising the same | 量子基因公司 | 2021-07-23 | — | — | CN | disclosed |