Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307286 | 0.88 | ADRA1A (0.42) | SMN1; SMN2IDO1 | |
| SCHEMBL8638637 | 0.86 | L3MBTL1 (0.44) | SMN1; SMN2ALOX5IDO1 | |
| SCHEMBL8456049 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL8290989 | 0.80 | TAAR1 (0.40) | CMA1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL8397899 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL562623 | 0.78 | LTA4H (0.39) | CMA1ALDH1A1IDO1 | |
| SCHEMBL28596361 | 0.78 | TSHR (0.43) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL6030733 | 0.78 | CA1 (0.44) | ALDH1A1NPC1RAB9AHPGDALOX15 | |
| SCHEMBL14812951 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL7290855 | 0.77 | ALDH1A1 (0.47) | CMA1ALDH1A1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658897-A | MUSCLE RELAXANTS AND OCULAR HYPOTENSIVE AGENTS | ALLERGAN (US) | 1997-08-19 | — | — | US | disclosed |