Sugi Predict

Sugi Predict / Compounds / SCHEMBL969878

SCHEMBL969878

SCHEMBL969878

O=[PH](Cc1ccccc1)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.46
▸ IDO1 P14902 1/20 0.43
▸ AGXT P21549 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ L3MBTL1 Q9Y468 3/20 0.39
▸ MAOB P27338 2/20 0.39
▸ SLC6A2 P23975 2/20 0.39
▸ SLC6A3 Q01959 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ MAOA P21397 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ LOXL2 Q9Y4K0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7051790 0.89 NPC1 (0.43) TSHRAGXTALDH1A1CA1CA2
SCHEMBL1631357 0.81 TSHR (0.44) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL563886 0.81 TP53 (0.41) TSHRIDO1ALDH1A1MAOBSMN1; SMN2
SCHEMBL698616 0.80 TSHR (0.48) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL10841134 0.79 TSHR (0.40) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL29806030 0.79 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL36370 0.79 TSHR (0.52) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL12724016 0.79 TSHR (0.54) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL28596361 0.79 TSHR (0.43) TSHRIDO1AGXTALDH1A1CA1
SCHEMBL15961256 0.78 TSHR (0.46) TSHRIDO1AGXTALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1238423-C Thermoplastic resin composition and molded object thereof POLYPLASTICS CO (JP) 2006-01-25 — — CN claimed
US-10874673-B2 Inhibitors of influenza viruses replication VERTEX PHARMACEUTICALS INCORPORATED (US) 2020-12-29 — — US disclosed
EP-3500544-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS Huntsman Petrochemical LLC (US) 2019-06-26 — — EP disclosed
US-20190161418-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS INDORAMA VENTURES OXIDES LLC 2019-05-30 — — US disclosed
CN-109563249-A The polymer blend comprising tetramethylcyclobutanediol and ethylene glycol for calendering 伊士曼化工公司 2019-04-02 — — CN disclosed
CN-109071371-A The soluble plant micronutrient of oil 亨斯迈石油化学有限责任公司 2018-12-21 — — CN disclosed
US-10039762-B2 Inhibitors of influenza viruses replication VERTEX PHARMACEUTICALS INCORPORATED (US) 2018-08-07 — — US disclosed
US-20180078553-A1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMACEUTICALS INCORPORATED 2018-03-22 — — US disclosed
WO-2018034864-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS HUNTSMAN PETROCHEMICAL LLC (US) 2018-02-22 — — WO disclosed
US-9822425-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2017-11-21 — — US disclosed
US-20120171245-A1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMACEUTICALS INCORPORATED (US) 2012-07-05 — — US disclosed
EP-2451985-A2 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS Cytec Technology Corporation (US) 2012-05-16 — — EP disclosed
US-20110005354-A1 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2011-01-13 — — US disclosed
WO-2011005736-A2 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2011-01-13 — — WO disclosed
CN-101384669-A Thermoplastic resin composition and liquid crystal display part or information recording medium part using the composition POLYPLASTICS CO (JP) 2009-03-11 — — CN disclosed
CN-101041669-A Non nucleoside reverse transcriptase inhibitors GILEAD SCIENCES INC (US) 2007-09-26 — — CN disclosed
CN-1828383-A Liquid crystal display component POLYPLASTICS CO (JP) 2006-09-06 — — CN disclosed
CN-1238423-C Thermoplastic resin composition and molded object thereof POLYPLASTICS CO (JP) 2006-01-25 — — CN disclosed
CN-1656109-A Non-nucleoside reverse transcriptase inhibitors GILEAD SCIENCES INC (US) 2005-08-17 — — CN disclosed
CN-1361810-A Thermoplastic resin composition and molded object thereof POLYPLASTICS CO (JP) 2002-07-31 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180078553-A1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION ACE, IRF3, ACE2 TSHR 2310/4885IDO1 20/4885AGXT 2580/4885
US-10874673-B2 Inhibitors of influenza viruses replication ACE, IRF3, ACE2 TSHR 2310/4885IDO1 20/4885AGXT 2580/4885
US-20120171245-A1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION ACE, IRF3, ACE2 TSHR 2310/4885IDO1 20/4885AGXT 2580/4885
US-20190161418-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS PNPO, SLC19A1, SLC6A12 TSHR 1640/4885IDO1 1198/4885AGXT 481/4885
US-10039762-B2 Inhibitors of influenza viruses replication ACE, IRF3, ACE2 TSHR 2310/4885IDO1 20/4885AGXT 2580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.