SCHEMBL28596407

SCHEMBL28596407

Cc1cc(Cl)ccc1C=CCO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
CYP3A4 P08684 2/20 0.35
ALDH1A1 P00352 4/20 0.35
RECQL P46063 1/20 0.35
NOX1 Q9Y5S8 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
MAPT P10636 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
MAPK1 P28482 1/20 0.34
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28603277 1.00 ALOX5 (0.37) ALOX5PTGS1PTGS2CYP3A4ALDH1A1
SCHEMBL18305079 0.81 CYP3A4 (0.38) ALOX5PTGS1PTGS2CYP3A4ALDH1A1
SCHEMBL4632456 0.81 NPC1 (0.43) ALOX5PTGS1PTGS2CYP3A4ALDH1A1
SCHEMBL3605644 0.81 TDP1 (0.50) ALDH1A1TDP1KMT2AKDM4EMEN1
SCHEMBL3605648 0.81 TDP1 (0.50) ALDH1A1TDP1KMT2AKDM4EMEN1
SCHEMBL4632454 0.81 NPC1 (0.43) ALOX5PTGS1PTGS2CYP3A4ALDH1A1
SCHEMBL22145213 0.78 NPC1 (0.37) CYP3A4ALDH1A1RECQLTDP1KMT2A
SCHEMBL22122733 0.78 NPC1 (0.37) CYP3A4ALDH1A1RECQLTDP1KMT2A
SCHEMBL28605482 0.78 ALDH1A1 (0.35) CYP3A4ALDH1A1RECQLKDM4EMAPT
SCHEMBL17495221 0.78 HDAC3 (0.42) PTGS1PTGS2CYP3A4ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113135816-A Method for synthesizing photoactive bromohydrin compound 常州大学 2021-07-20 CN disclosed