SCHEMBL28605482

SCHEMBL28605482

Cc1cc(Br)ccc1C=CCO

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
CYP3A4 P08684 1/20 0.35
RECQL P46063 1/20 0.35
RXFP1 Q9HBX9 2/20 0.35
HPGD P15428 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
MPO P05164 1/20 0.33
CASP1 P29466 1/20 0.33
ERN1 O75460 1/20 0.32
KDM4E B2RXH2 2/20 0.32
GAA P10253 1/20 0.32
SIGMAR1 Q99720 2/20 0.32
PYCR1 P32322 1/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28598576 1.00 ALDH1A1 (0.35) ALDH1A1CYP3A4RECQLRXFP1HPGD
SCHEMBL22881690 0.83 RXFP1 (0.35) ALDH1A1RXFP1HPGDMPOPYCR1
SCHEMBL4632454 0.81 NPC1 (0.43) ALDH1A1CYP3A4RECQLKDM4EMAPT
SCHEMBL4632456 0.81 NPC1 (0.43) ALDH1A1CYP3A4RECQLKDM4EMAPT
SCHEMBL22636002 0.79 RXFP1 (0.33) ALDH1A1RXFP1MPOCASP1KDM4E
SCHEMBL22647280 0.79 RXFP1 (0.33) ALDH1A1RXFP1MPOCASP1KDM4E
SCHEMBL28596407 0.78 ALOX5 (0.37) ALDH1A1CYP3A4RECQLKDM4EGAA
SCHEMBL8956862 0.78 GPR183 (0.39) ALDH1A1CYP3A4RECQLCASP1ERN1
SCHEMBL8956869 0.78 GPR183 (0.39) ALDH1A1CYP3A4RECQLCASP1ERN1
SCHEMBL28603277 0.78 ALOX5 (0.37) ALDH1A1CYP3A4RECQLKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113135816-A Method for synthesizing photoactive bromohydrin compound 常州大学 2021-07-20 CN disclosed