SCHEMBL28596457

SCHEMBL28596457

Cc1cc(-c2ccc(-c3cccc4cc5ccccc5cc34)cc2)c(N)c(-c2ccc(-c3cccc4cc5ccccc5cc34)cc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 1/20 0.38
ENPP3 O14638 1/20 0.37
ENPP1 P22413 1/20 0.37
TLR8 Q9NR97 1/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.37
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
PSMB5 P28074 1/20 0.36
PPARG P37231 5/20 0.35
PPARA Q07869 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30001147 0.87 CYP1A2 (0.40) NUDT1MEN1KMT2ANPC1RAB9A
SCHEMBL28596459 0.87 CYP1A2 (0.40) NUDT1MEN1KMT2ANPC1RAB9A
SCHEMBL7055518 0.84 MEN1 (0.45) MEN1KMT2ANPC1RAB9ACYP1A2
SCHEMBL28795643 0.83 MEN1 (0.44) MEN1KMT2ANPC1RAB9ACYP1A2
SCHEMBL537003 0.82 ALDH1A1 (0.44) MEN1KMT2AENPP3ENPP1TLR8
SCHEMBL5471388 0.81 PRKCZ (0.47) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL27558874 0.81 CYP1A2 (0.44) MEN1KMT2ANPC1RAB9ACYP1A2
SCHEMBL7267293 0.81 CYP1A2 (0.46) CYP1A2CYP2A6ENPP3ENPP1TLR8
SCHEMBL27675918 0.78 TNF (0.47) MEN1KMT2ACYP1A2ALDH1A1KDM4E
SCHEMBL30657223 0.78 CYP1A2 (0.48) MEN1KMT2ACYP1A2CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113135828-B Aromatic amine, alpha-diimine ligand and nickel catalyst based on rigid terphenyl structure and preparation method and application thereof 中国科学院长春应用化学研究所 2022-11-22 CN disclosed
CN-113135828-A Aromatic amine, alpha-diimine ligand and nickel catalyst based on rigid terphenyl structure and preparation method and application thereof 中国科学院长春应用化学研究所 2021-07-20 CN disclosed