SCHEMBL537003

SCHEMBL537003

c1ccc2cc3c(-c4ccc(-c5cccc6cc7ccccc7cc56)cc4)cccc3cc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 3/20 0.44
HPGD P15428 3/20 0.44
TSHR P16473 2/20 0.44
MAPK1 P28482 2/20 0.44
CASP1 P29466 2/20 0.44
TP53 P04637 1/20 0.44
CASP7 P55210 1/20 0.44
KDM4E B2RXH2 3/20 0.44
GAA P10253 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
TNF P01375 1/20 0.42
CYP1B1 Q16678 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27675918 0.95 TNF (0.47) ALDH1A1HIF1AHSD17B10HPGDTSHR
SCHEMBL27675530 0.94 CA12 (0.51) ALDH1A1HIF1AHSD17B10HPGDTSHR
SCHEMBL5713441 0.94 TNF (0.47) ALDH1A1HIF1AHSD17B10HPGDTSHR
Biphenyl SCHEMBL27587049 0.94 TNF (0.47) ALDH1A1HIF1AHSD17B10HPGDTSHR
SCHEMBL60347 0.93 TNF (0.50) ALDH1A1HIF1AHSD17B10HPGDTSHR
SCHEMBL30332794 0.93 TNF (0.50) ALDH1A1HIF1AHSD17B10HPGDTSHR
SCHEMBL17443013 0.92 TNF (0.46) ALDH1A1HIF1AHSD17B10HPGDTSHR
SCHEMBL23327305 0.91 TNF (0.48) ALDH1A1HIF1AHSD17B10HPGDTSHR
SCHEMBL1309613 0.91 TNF (0.48) ALDH1A1HIF1AHSD17B10HPGDTSHR
Hydrogen Sulfide SCHEMBL9349313 0.91 TNF (0.48) ALDH1A1HIF1AHSD17B10HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10243145-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2019-03-26 US claimed
EP-2199361-B2 Organic electroluminescent devices and organic luminescent medium IDEMITSU KOSAN CO (JP) 2016-06-15 EP claimed
US-20130328030-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2013-12-12 US claimed
US-20130069523-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM MATSUURA MASAHIDE (JP) 2013-03-21 US claimed
US-8334648-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2012-12-18 US claimed
US-8324802-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN, CO., LTD. (JP) 2012-12-04 US claimed
EP-2199361-B9 Organic electroluminescent devices and organic luminescent medium IDEMITSU KOSAN CO (JP) 2012-02-08 EP claimed
EP-2199361-B1 Organic electroluminescent devices and organic luminescent medium IDEMITSU KOSAN CO (JP) 2011-10-19 EP claimed
US-7927716-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN, CO., LTD. (JP) 2011-04-19 US claimed
US-20100277061-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2010-11-04 US claimed
US-20100270913-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2010-10-28 US claimed
US-7732063-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN, CO., LTD. (JP) 2010-06-08 US claimed
US-7705183-B2 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2010-04-27 US claimed
US-7651786-B2 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN, CO., LTD. (JP) 2010-01-26 US claimed
EP-1953166-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-08-06 EP claimed
US-20070237984-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC LIGHT EMITTING MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2007-10-11 US claimed
US-20070114917-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-05-24 US claimed
US-20060033421-A1 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2006-02-16 US claimed
EP-1541657-A1 ORGANIC ELECTROLUMINESCENT DEVICES AND ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. (JP) 2005-06-15 EP claimed
US-20050064233-A1 Organic electroluminescence device and organic light emitting medium IDEMITSU KOSAN CO., LTD. (JP) 2005-03-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070114917-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME EML4, MAOA, TYR ALDH1A1 382/4885HIF1A 4383/4885HSD17B10 2777/4885
US-10243145-B2 Organic electroluminescence device and organic light emitting medium TRPA1, EPM2A, KCNN2 ALDH1A1 47/4885HIF1A 4426/4885HSD17B10 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.