Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.43 |
| ▸ | GCK | P35557 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597283 | 0.79 | SGMS2 (0.43) | SGMS2SGMS1GCKPKMSMN1; SMN2 | |
| SCHEMBL488883 | 0.73 | SGMS2 (0.56) | SGMS2SGMS1GCKPKMSMN1; SMN2 | |
| SCHEMBL2337781 | 0.72 | GCK (0.71) | GCKGRM5 | |
| SCHEMBL488951 | 0.70 | NPC1 (0.61) | SGMS2SGMS1PKMSMN1; SMN2MET | |
| SCHEMBL487772 | 0.68 | PTGER1 (0.33) | SGMS2SGMS1PKMSMN1; SMN2MET | |
| SCHEMBL488725 | 0.67 | NPC1 (0.66) | SGMS2SMN1; SMN2 | |
| SCHEMBL488950 | 0.66 | MET (0.57) | MET | |
| SCHEMBL488882 | 0.66 | GABRP (0.44) | — | |
| SCHEMBL9126866 | 0.66 | PPIA (0.52) | SGMS2SGMS1SMN1; SMN2PPIA | |
| SCHEMBL9126609 | 0.66 | PPIA (0.53) | SGMS2SGMS1PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-113181362-A | Agent for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2021-07-30 | — | — | CN | disclosed |