Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 3/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.40 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.40 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596989 | 1.00 | KMT2A (0.47) | KMT2AMEN1MAPTPLA2G6PLA2G4A | |
| SCHEMBL28596988 | 1.00 | KMT2A (0.47) | KMT2AMEN1MAPTPLA2G6PLA2G4A | |
| SCHEMBL480910 | 0.84 | KMT2A (0.47) | KMT2AMEN1MAPTGRM8GRM1 | |
| SCHEMBL4592036 | 0.79 | KMT2A (0.46) | KMT2AMEN1MAPTGRM8GRM1 | |
| SCHEMBL23563177 | 0.77 | PRKCA (0.47) | TSHRLYPLA1LYPLA2ABHD16A | |
| SCHEMBL14581339 | 0.77 | PRKCA (0.47) | TSHRLYPLA1LYPLA2ABHD16A | |
| SCHEMBL6125509 | 0.76 | KMT2A (0.51) | KMT2AMEN1MAPTGRM8GRM1 | |
| Propionamide SCHEMBL28290130 | 0.76 | GRM8 (0.48) | KMT2AMEN1MAPTGRM8GRM1 | |
| Nonane SCHEMBL27663344 | 0.75 | GAA (0.56) | KMT2AMEN1MAPTGRM8GRM1 | |
| SCHEMBL10481361 | 0.75 | KMT2A (0.44) | KMT2AMEN1MAPTGRM8GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105422-B | Preparation method of trans-3,4-diaryl dihydrocoumarin compound | 温州大学新材料与产业技术研究院 | 2022-10-28 | — | — | CN | claimed |
| CN-113105422-A | Preparation method of trans-3, 4-diaryl dihydrocoumarin compound | 温州大学新材料与产业技术研究院 | 2021-07-13 | — | — | CN | claimed |
| CN-113105422-B | Preparation method of trans-3,4-diaryl dihydrocoumarin compound | 温州大学新材料与产业技术研究院 | 2022-10-28 | — | — | CN | disclosed |
| CN-113105422-B | Preparation method of trans-3,4-diaryl dihydrocoumarin compound | 温州大学新材料与产业技术研究院 | 2022-10-28 | — | — | CN | disclosed |
| CN-113105422-B | Preparation method of trans-3,4-diaryl dihydrocoumarin compound | 温州大学新材料与产业技术研究院 | 2022-10-28 | — | — | CN | disclosed |
| CN-113105422-A | Preparation method of trans-3, 4-diaryl dihydrocoumarin compound | 温州大学新材料与产业技术研究院 | 2021-07-13 | — | — | CN | disclosed |
| CN-113105422-A | Preparation method of trans-3, 4-diaryl dihydrocoumarin compound | 温州大学新材料与产业技术研究院 | 2021-07-13 | — | — | CN | disclosed |
| CN-113105422-A | Preparation method of trans-3, 4-diaryl dihydrocoumarin compound | 温州大学新材料与产业技术研究院 | 2021-07-13 | — | — | CN | disclosed |