Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611023 | 0.80 | TUBB4A (0.50) | SMOMAPK1NPC1RAB9AROCK2 | |
| SCHEMBL28606427 | 0.80 | TDP1 (0.51) | MAPK1KDM4EROCK2ROCK1MAPK3 | |
| SCHEMBL28608113 | 0.77 | HDAC1 (0.56) | SMOMAPK1ALDH1A1MAPK3HDAC6 | |
| SCHEMBL28601933 | 0.77 | HDAC1 (0.58) | SMPD1MAPK1L3MBTL1ROCK2ROCK1 | |
| SCHEMBL28601974 | 0.75 | MEN1 (0.61) | MAPK1HIF1AGAANPC1RAB9A | |
| SCHEMBL355292 | 0.74 | PTPN1 (0.63) | PTPN1SMPD1HIF1AGAAKDM4E | |
| SCHEMBL28598671 | 0.73 | CTSA (0.59) | MAPK1HIF1AROCK2ROCK1MAPK3 | |
| SCHEMBL28597825 | 0.72 | HIF1A (0.67) | PTPN1SMOSMPD1MAPK1HIF1A | |
| SCHEMBL693635 | 0.71 | SMPD1 (0.50) | SMPD1MAPK1GAAPOLBRAB9A | |
| SCHEMBL12757878 | 0.71 | PTPN1 (0.63) | PTPN1HIF1AGAAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |