Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606427 | 0.79 | TDP1 (0.51) | MAPK3MAPK1KMT2AS1PR1S1PR3 | |
| SCHEMBL28608113 | 0.79 | HDAC1 (0.56) | HDAC1HDAC6HDAC8MAPK3MAPK1 | |
| SCHEMBL28597828 | 0.77 | PTPN1 (0.48) | HDAC6SMPD1MAPK3MAPK1L3MBTL1 | |
| SCHEMBL2104880 | 0.75 | HDAC6 (0.77) | HDAC1HDAC6HDAC8SMPD1TSHR | |
| SCHEMBL28601974 | 0.74 | MEN1 (0.61) | MAPK3MAPK1KMT2AMEN1ROCK2 | |
| SCHEMBL28598671 | 0.73 | CTSA (0.59) | MAPK3MAPK1KMT2AMEN1ROCK2 | |
| SCHEMBL28601931 | 0.72 | HDAC1 (0.59) | HDAC1HDAC6HDAC8SMPD1TSHR | |
| SCHEMBL2559848 | 0.72 | HDAC6 (0.77) | HDAC1HDAC6HDAC8SMPD1TSHR | |
| SCHEMBL28611023 | 0.71 | TUBB4A (0.50) | HDAC1HDAC6HDAC8MAPK3MAPK1 | |
| SCHEMBL14959517 | 0.70 | HDAC6 (0.68) | HDAC1HDAC6HDAC8SMPD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |