Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598671 | 0.83 | CTSA (0.59) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28601296 | 0.83 | BAZ2B (0.58) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4067128 | 0.77 | ALDH1A1 (0.71) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28606427 | 0.77 | TDP1 (0.51) | KMT2AROCK2ROCK1MAPK1LMNA | |
| SCHEMBL5643696 | 0.77 | MEN1 (0.75) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10013613 | 0.76 | CYP1A2 (1.00) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28374426 | 0.76 | SMN1; SMN2 (0.51) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17753762 | 0.76 | L3MBTL1 (0.50) | ROCK2ROCK1MAPK1MAPK3NPC1 | |
| SCHEMBL28597828 | 0.75 | PTPN1 (0.48) | ROCK2ROCK1MAPK1LMNAMAPK3 | |
| SCHEMBL2413088 | 0.75 | ROCK2 (0.68) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |