Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858186 | 0.73 | KMT2A (0.48) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL6316045 | 0.71 | TSHR (0.58) | KMT2ANPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL18765244 | 0.71 | GAA (0.57) | KMT2ANPC1RAB9AL3MBTL1LIPE | |
| SCHEMBL2857154 | 0.71 | KMT2A (0.55) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL4978171 | 0.71 | ALOX5AP (0.42) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL6644466 | 0.71 | CYP2D6 (0.46) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL18765408 | 0.70 | GAA (0.56) | KMT2ANPC1RAB9AL3MBTL1LIPE | |
| SCHEMBL10962248 | 0.70 | POLQ (0.43) | KMT2ANPC1RAB9AL3MBTL1LIPE | |
| SCHEMBL762423 | 0.69 | ALDH1A1 (0.50) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL243741 | 0.69 | POLB (0.51) | KMT2AMEN1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |