Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2860376 | 0.90 | PNMT (0.35) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL8509884 | 0.88 | PNMT (0.33) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL650444 | 0.85 | NPC1 (0.39) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL3124487 | 0.80 | NPC1 (0.49) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL8510211 | 0.79 | PNMT (0.33) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL1236216 | 0.79 | NPC1 (0.36) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL2860380 | 0.79 | NPC1 (0.36) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL820432 | 0.77 | NPC1 (0.36) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL674549 | 0.77 | NPC1 (0.33) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL673106 | 0.77 | NPC1 (0.33) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661921-B1 | Synthetic lubricating oil and lubricating oil composition thereof | MITSUI CHEMICALS INC (JP) | 2019-07-17 | — | — | EP | disclosed |
| EP-2570472-A1 | LUBRICATING OIL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-20120135903-A1 | LUBRICATING OIL COMPOSITION | MITSUI CHEMICALS, INC. | 2012-05-31 | — | — | US | disclosed |
| US-7795194-B2 | Synthetic lubricating oil and lubricating oil composition | MITSUI CHEMICALS, INC. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20060116303-A1 | decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability | MITSUI CHEMICALS, INC. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1661921-A1 | Synthetic lubricating oil and lubricating oil composition thereof | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |