Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL216652 | 0.85 | NPC1 (0.40) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL1235499 | 0.84 | NPC1 (0.39) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL650444 | 0.83 | NPC1 (0.39) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL6554724 | 0.83 | NPC1 (0.39) | NPC1RAB9APNMTHTR2BHTR7 | |
| SCHEMBL4577365 | 0.82 | NPC1 (0.40) | NPC1RAB9APNMTHTR2BHTR7 | |
| Fluoride Ion SCHEMBL1130885 | 0.82 | NPC1 (0.40) | NPC1RAB9APNMTHTR2BHTR7 | |
| Bromide SCHEMBL7930572 | 0.82 | NPC1 (0.40) | NPC1RAB9APNMTHTR2BHTR7 | |
| Iodide SCHEMBL7931400 | 0.82 | NPC1 (0.40) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL6553935 | 0.82 | NPC1 (0.38) | NPC1RAB9APNMTHTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL648411 | 0.81 | NPC1 (0.37) | NPC1RAB9APNMTHTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398167-B2 | Process for producing metallocenes | LANXESS ORGANOMETALLICS GMBH (DE) | 2025-08-26 | — | — | US | disclosed |
| EP-3917938-A1 | PROCESS FOR PRODUCING METALLOCENES | LANXESS Organometallics GmbH (DE) | 2021-12-08 | — | — | EP | disclosed |
| CN-113366004-A | Process for producing metallocenes | 朗盛奥诺麦特里克斯有限责任公司 | 2021-09-07 | — | — | CN | disclosed |
| WO-2020156998-A1 | PROCESS FOR PRODUCING METALLOCENES | LANXESS ORGANOMETALLICS GMBH (DE) | 2020-08-06 | — | — | WO | disclosed |
| EP-3686209-A1 | PROCESS FOR PRODUCING METALLOCENES | LANXESS Organometallics GmbH (DE) | 2020-07-29 | — | — | EP | disclosed |
| US-9919300-B2 | 1-hexene production process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-20 | — | — | US | disclosed |
| EP-2484685-B1 | TRANSITION METAL COMPLEX, PREPARATION METHOD FOR SAID TRANSITION METAL COMPLEX, TRIMERIZATION CATALYST, PREPARATION METHOD FOR 1-HEXENE, PREPARATION METHOD FOR ETHYLENE POLYMER, SUBSTITUTED CYCLOPENTADIENE COMPOUND, AND PREPARATION METHOD FOR SAID SUBSTITUTED CYCLOPENTADIENE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-11-01 | — | — | EP | disclosed |
| US-20170036200-A1 | 1-HEXENE PRODUCTION PROCESS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-09 | — | — | US | disclosed |
| US-20150105572-A1 | TRANSITION METAL COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-04-16 | — | — | US | disclosed |
| US-20150105237-A1 | CATALYTIC COMPONENT FOR TRIMERIZATION AND TRIMERIZATION CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-04-16 | — | — | US | disclosed |
| US-7393907-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2008-07-01 | — | — | US | disclosed |
| EP-1734061-A2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1186619-B1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof | MITSUI CHEMICALS INC (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6984743-B1 | Method for producing metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2006-01-10 | — | — | US | disclosed |
| US-20040122192-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. | 2004-06-24 | — | — | US | disclosed |
| US-20020156207-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1186619-A2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof | Mitsui Chemicals, Inc. (JP) | 2002-03-13 | — | — | EP | disclosed |
| EP-0604908-B1 | Process for the polymerisation of alpha-olefins using metallocene compounds having ligands of fluorenylic type | BASELL TECHNOLOGY CO BV (NL) | 2001-09-19 | — | — | EP | disclosed |
| EP-0942006-A2 | Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst | TOSOH CORPORATION (JP) | 1999-09-15 | — | — | EP | disclosed |
| EP-0604908-A2 | Metallocene compounds having ligands of fluorenylic type | Montell Technology Company bv (NL) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036200-A1 | 1-HEXENE PRODUCTION PROCESS | AP1M1, HK1, CYC1 | SLC6A2 4851/4885NPC1 4361/4885RAB9A 2832/4885 |
| US-20150105572-A1 | TRANSITION METAL COMPLEX | AP1M1, AP3M1, EMC1 | SLC6A2 4808/4885NPC1 3786/4885RAB9A 2371/4885 |
| US-12398167-B2 | Process for producing metallocenes | CYP4F2, PRDX2, PRXL2A | SLC6A2 4818/4885NPC1 3267/4885RAB9A 4723/4885 |
| US-20150105237-A1 | CATALYTIC COMPONENT FOR TRIMERIZATION AND TRIMERIZATION CATALYST | AP1M1, AMY1A, AP3M1 | SLC6A2 4885/4885NPC1 4608/4885RAB9A 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.