Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662956 | 0.85 | CCNC (0.43) | PDK2LMNAL3MBTL1BTKKMT2A | |
| SCHEMBL19087047 | 0.82 | HTT (0.60) | PDK2LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL18869380 | 0.81 | L3MBTL1 (0.41) | LMNAHTTSMN1; SMN2L3MBTL1GAA | |
| SCHEMBL23120471 | 0.80 | L3MBTL1 (0.46) | PDK2LMNASMN1; SMN2L3MBTL1BTK | |
| SCHEMBL28603762 | 0.80 | PDK2 (0.42) | PDK2LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL19116732 | 0.79 | HTT (0.45) | PDK2LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL19077855 | 0.79 | PDK2 (0.44) | PDK2LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL671192 | 0.77 | PDK2 (0.45) | PDK2LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16245541 | 0.75 | TSHR (0.41) | L3MBTL1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL16245549 | 0.75 | ALDH1A1 (0.48) | LMNAHTTSMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135913-B | 3-substituent-6-pyridine substituent-six-membered and five-membered heterocyclic derivative and preparation method and application thereof | 沈阳药科大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113135913-A | 3-substituent-6-pyridine substituent-six-membered and five-membered heterocyclic derivative and preparation method and application thereof | 沈阳药科大学 | 2021-07-20 | — | — | CN | disclosed |