Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 18/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28918149 | 0.90 | USP30 (0.46) | USP30 | |
| SCHEMBL28592396 | 0.88 | DRD2 (0.45) | USP30DRD2DRD4DRD3UCHL1 | |
| SCHEMBL28603773 | 0.86 | USP30 (0.50) | USP30DRD2DRD4DRD3UCHL1 | |
| SCHEMBL28592627 | 0.83 | USP30 (0.48) | USP30DRD2DRD4DRD3UCHL1 | |
| SCHEMBL28586425 | 0.80 | USP30 (0.49) | USP30UCHL1 | |
| SCHEMBL28590775 | 0.78 | USP30 (0.59) | USP30UCHL1 | |
| SCHEMBL28586845 | 0.78 | USP30 (0.59) | USP30UCHL1 | |
| SCHEMBL28586426 | 0.78 | USP30 (0.53) | USP30 | |
| SCHEMBL28586992 | 0.77 | USP30 (0.53) | USP30UCHL1 | |
| SCHEMBL28586848 | 0.76 | USP30 (0.56) | USP30UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884068-B | 1-cyano-pyrrolidine derivatives as DUB inhibitors | 特殊治疗有限公司 | 2021-02-26 | — | — | CN | disclosed |