Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606352 | 0.94 | AR (0.42) | ARGRIK1P2RX1P2RX4P2RX7 | |
| SCHEMBL28604163 | 0.89 | GRIK1 (0.43) | ARGRIK1P2RX1P2RX4P2RX7 | |
| SCHEMBL28600917 | 0.88 | GRIK1 (0.39) | GRIK1ALDH1A1CNR1KDR | |
| SCHEMBL28611460 | 0.88 | ALDH1A1 (0.41) | ALDH1A1CNR1KDR | |
| SCHEMBL28611473 | 0.88 | KDR (0.38) | P2RX1P2RX4P2RX7TMPRSS4KDR | |
| SCHEMBL28610950 | 0.85 | IDH1 (0.41) | ARGRIK1P2RX1P2RX4P2RX7 | |
| SCHEMBL28608062 | 0.85 | GRIK1 (0.40) | ARGRIK1P2RX1P2RX4P2RX7 | |
| SCHEMBL28612432 | 0.84 | RAB9A (0.42) | ALDH1A1KDR | |
| SCHEMBL28919914 | 0.84 | MEN1 (0.43) | ARALDH1A1CNR1 | |
| SCHEMBL28612681 | 0.83 | IDH1 (0.42) | ARGRIK1P2RX1P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |