Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28608385 | 0.92 | KDM4E (0.43) | RAB9AJAK3NPC1MAPTKMT2A | |
| SCHEMBL28608529 | 0.90 | RAB9A (0.38) | RAB9AJAK3NPC1MAPTKMT2A | |
| SCHEMBL28611473 | 0.89 | KDR (0.38) | RAB9AMAPTKMT2ASMN1; SMN2KDR | |
| SCHEMBL28611460 | 0.87 | ALDH1A1 (0.41) | RAB9ANPC1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL28600917 | 0.87 | GRIK1 (0.39) | RAB9AJAK3NPC1MAPTKMT2A | |
| SCHEMBL28608069 | 0.86 | JAK3 (0.42) | RAB9AJAK3NPC1MAPTKMT2A | |
| SCHEMBL28601575 | 0.86 | JAK3 (0.42) | RAB9AJAK3NPC1MAPTKMT2A | |
| SCHEMBL28599130 | 0.84 | AR (0.44) | ALDH1A1KDR | |
| SCHEMBL28919914 | 0.84 | MEN1 (0.43) | RAB9AMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28600852 | 0.83 | HTT (0.43) | MAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |