Cinnamaldehyde

Cinnamaldehyde

SCHEMBL28599267

O=C/C=C/c1ccccc1.O=C/C=C/c1ccccc1.SS

nearest known ligand 0.90

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.90
LMNA P02545 2/20 0.90
MAPK1 P28482 2/20 0.90
TRPA1 O75762 1/20 0.90
ALOX5 P09917 1/20 0.90
MAOB P27338 1/20 0.62
MAPT P10636 3/20 0.54
KDM4E B2RXH2 1/20 0.54
CDK4 P11802 3/20 0.52
CCND1 P24385 3/20 0.52
CCNB2 O95067 2/20 0.52
CDK1 P06493 2/20 0.52
CCNB1 P14635 2/20 0.52
CCNB3 Q8WWL7 2/20 0.52
CYP2A6 P11509 1/20 0.48
CMA1 P23946 1/20 0.47
HDAC3 O15379 2/20 0.45
HDAC4 P56524 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC7 Q8WUI4 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnamaldehyde SCHEMBL3441 0.95 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL28377503 0.95 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamic Aldehyde SCHEMBL159856 0.95 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL3442 0.95 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL2203965 0.95 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL25267814 0.95 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL28377500 0.95 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamic Aldehyde SCHEMBL1866630 0.95 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1TRPA1ALOX5
Biphenyl SCHEMBL4693704 0.93 ALDH1A1 (0.86) ALDH1A1LMNAMAPK1TRPA1ALOX5
Cinnamaldehyde SCHEMBL11865695 0.92 ALDH1A1 (0.95) ALDH1A1LMNAMAPK1TRPA1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111718465-B Poly-dithioacetal and preparation method and application thereof 华南理工大学 2021-07-20 CN claimed