Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31181776 | 1.00 | KDM1A (0.32) | KDM1AKCNH2RCOR1HRH4HRH3 | |
| SCHEMBL20281866 | 0.71 | HRH3 (0.44) | KDM1AKCNH2RCOR1HRH4HRH3 | |
| SCHEMBL28576568 | 0.68 | SSTR4 (0.31) | SSTR4CHRM1CHRNB2CHRNA4 | |
| SCHEMBL28576571 | 0.68 | SSTR4 (0.31) | SSTR4CHRM1CHRNB2CHRNA4 | |
| SCHEMBL17303549 | 0.67 | P2RX7 (0.40) | KCNH2BRD4 | |
| SCHEMBL28434263 | 0.65 | SLC6A1 (0.39) | — | |
| SCHEMBL28731213 | 0.64 | KDM1A (0.46) | KDM1AKCNH2RCOR1 | |
| SCHEMBL2942079 | 0.63 | CYP2D6 (0.43) | CHRM3 | |
| SCHEMBL27498224 | 0.62 | KDM1A (0.38) | KDM1AKCNH2CHRM3CHRM2CHRM1 | |
| SCHEMBL1081079 | 0.62 | GABRA5 (0.45) | KCNH2HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996785-A | Therapeutic compounds | 希四克斯探索有限公司 | 2021-06-18 | — | — | CN | disclosed |