Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.85 |
| ▸ | TSHR | P16473 | 5/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | PPARD | Q03181 | 6/20 | 0.58 |
| ▸ | PPARA | Q07869 | 6/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TLR2 | O60603 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL1963560 | 0.96 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL518168 | 0.96 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL515200 | 0.96 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL401737 | 0.96 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrochloric Acid SCHEMBL525656 | 0.92 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL687821 | 0.92 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrochloric Acid SCHEMBL14809119 | 0.92 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL8066502 | 0.92 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrochloric Acid SCHEMBL8920429 | 0.92 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| SCHEMBL6049863 | 0.92 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105563-A | Method for preparing Cellulose Nanofibrils (CNF) through metal salt/organic acid synergistic treatment | 天津科技大学 | 2021-07-13 | — | — | CN | disclosed |