SCHEMBL28599537

SCHEMBL28599537

[c]1ccc(-c2ccc3oc4ccc(-c5ncccn5)cc4c3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.38
MAPT P10636 2/20 0.38
CLK4 Q9HAZ1 3/20 0.37
PLA2G2A P14555 2/20 0.34
PLA2G4A P47712 2/20 0.34
DYRK1A Q13627 2/20 0.33
PIK3CD O00329 1/20 0.33
PIP5K1C O60331 1/20 0.33
PI4KA P42356 1/20 0.33
PIK3CG P48736 1/20 0.33
PI4KB Q9UBF8 1/20 0.33
CDK9 P50750 1/20 0.33
DYRK2 Q92630 1/20 0.33
ADRB2 P07550 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28603687 0.85 NPC1 (0.38) NPC1MAPTPLA2G2APLA2G4APIK3CD
SCHEMBL28590587 0.83 DYRK1A (0.45) MAPTDYRK1AMAP4K4
SCHEMBL28598897 0.83 CLK4 (0.37) NPC1MAPTCLK4PLA2G2APLA2G4A
SCHEMBL29072333 0.83 KDM4E (0.45) NPC1MAPTPLA2G2APLA2G4ADYRK1A
SCHEMBL28596704 0.82 CYP2A6 (0.40) NPC1MAPTDYRK1ACDK9DYRK2
SCHEMBL28594945 0.82 PRMT5 (0.40) NPC1MAPTDYRK1ACDK9DYRK2
SCHEMBL10324400 0.81 MAPT (0.50) NPC1MAPTPLA2G2APLA2G4AKDM4E
SCHEMBL28586232 0.80 PGR (0.47) MAPTCLK4DYRK1APIK3CDPIK3CG
SCHEMBL18924707 0.80 MAPT (0.57) NPC1MAPTPLA2G2APLA2G4AKDM4E
SCHEMBL28590548 0.77 ATM (0.37) PLA2G2APLA2G4ADYRK1ACDK9DYRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed