SCHEMBL28596704

SCHEMBL28596704

Cc1cccnc1-c1ccc2oc3ccc(-c4cc[c]cc4)cc3c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.40
EPHX2 P34913 1/20 0.39
ABL1 P00519 1/20 0.36
CNR2 P34972 1/20 0.35
GRIA2 P42262 1/20 0.35
TRPV1 Q8NER1 6/20 0.35
HRH3 Q9Y5N1 1/20 0.34
CDK9 P50750 1/20 0.33
DYRK1A Q13627 1/20 0.33
DYRK2 Q92630 1/20 0.33
NPC1 O15118 3/20 0.33
MAPT P10636 1/20 0.33
SQOR Q9Y6N5 2/20 0.32
RAB9A P51151 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HAVCR2 Q8TDQ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28592108 0.86 CYP2A6 (0.40) CYP2A6EPHX2ABL1CNR2GRIA2
SCHEMBL28599537 0.82 NPC1 (0.38) CDK9DYRK1ADYRK2NPC1MAPT
SCHEMBL28594945 0.82 PRMT5 (0.40) ABL1CDK9DYRK1ADYRK2NPC1
SCHEMBL28596710 0.81 CYP2A6 (0.38) CYP2A6EPHX2ABL1CNR2GRIA2
SCHEMBL29072333 0.78 KDM4E (0.45) CDK9DYRK1ADYRK2NPC1MAPT
SCHEMBL1521697 0.78 CYP2A6 (0.56) CYP2A6CNR2GRIA2TRPV1SQOR
SCHEMBL28603687 0.77 NPC1 (0.38) CYP2A6NPC1MAPTRAB9AL3MBTL1
SCHEMBL28590587 0.75 DYRK1A (0.45) DYRK1AMAPT
SCHEMBL28586232 0.75 PGR (0.47) CYP2A6ABL1CDK9DYRK1AMAPT
SCHEMBL22921153 0.75 NPC1 (0.40) CYP2A6EPHX2CNR2TRPV1CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed