Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.74 |
| ▸ | ARG2 | P78540 | 4/20 | 0.47 |
| ▸ | ARG1 | P05089 | 3/20 | 0.47 |
| ▸ | NOS2 | P35228 | 6/20 | 0.46 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | NOS3 | P29474 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL29170023 | 1.00 | GSR (0.74) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL29244084 | 1.00 | GSR (0.74) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28193353 | 0.96 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28697152 | 0.96 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28185340 | 0.96 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL27006 | 0.96 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL273455 | 0.96 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL50314 | 0.96 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL28241453 | 0.96 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 | |
| Lysine SCHEMBL26606338 | 0.96 | GSR (0.80) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118286495-A | Fast-curing adhesive, and preparation method and application thereof | 诺一迈尔(山东)医学科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-117567790-B | Medical polyurethane foam with procoagulant inner surface and anticoagulant outer surface and preparation method thereof | 四川大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-115569244-B | Sandwich type degradable biological material and application thereof | 珠海睿展生物材料有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117567790-A | Medical polyurethane foam with procoagulant inner surface and anticoagulant outer surface and preparation method thereof | 四川大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-115427473-A | Color stable curing agent compositions comprising water dispersible polyisocyanates | 巴斯夫欧洲公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-108291002-B | Water-dispersible polyisocyanates | 巴斯夫欧洲公司 | 2021-07-23 | — | — | CN | disclosed |