Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28610225 | 0.89 | LMNA (0.44) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL28608762 | 0.89 | LMNA (0.44) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL28610232 | 0.84 | KMT2A (0.44) | MEN1KMT2AMAPTSMN1; SMN2TSHR | |
| SCHEMBL4906665 | 0.77 | LMNA (0.44) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11168519 | 0.75 | KMT2A (0.49) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30459416 | 0.74 | LMNA (0.47) | LMNAMAPTSMN1; SMN2NPSR1TSHR | |
| SCHEMBL432360 | 0.74 | LMNA (0.47) | LMNAMAPTSMN1; SMN2NPSR1TSHR | |
| Acetic Acid SCHEMBL28596119 | 0.74 | TDP1 (0.47) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7219984 | 0.74 | GAA (0.39) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| Acetic Acid SCHEMBL28592713 | 0.74 | TDP1 (0.47) | LMNAMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905802-B | Antifouling coating composition and coated article having coating film thereof | 关西涂料株式会社 | 2021-06-25 | — | — | CN | disclosed |