Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084592 | 0.82 | CUL4A (0.46) | GAANPC1RAB9AMAPTKDM4E | |
| SCHEMBL17466053 | 0.79 | KDM4E (0.42) | GAANPC1RAB9AMAPTKDM4E | |
| SCHEMBL28874050 | 0.79 | NPC1 (0.39) | GAANPC1 | |
| SCHEMBL8370837 | 0.78 | NPC1 (0.37) | GAANPC1RAB9AMAPTPOLB | |
| SCHEMBL7220398 | 0.78 | NPC1 (0.33) | NPC1RAB9AMAPTKDM4EPOLB | |
| SCHEMBL27298534 | 0.77 | NPC1 (0.36) | GAANPC1RAB9AMAPTPOLB | |
| Acetic Acid SCHEMBL28608762 | 0.75 | LMNA (0.44) | MAPTKDM4EPOLBSMN1; SMN2ALDH1A1 | |
| Acetic Acid SCHEMBL28610225 | 0.75 | LMNA (0.44) | MAPTKDM4EPOLBSMN1; SMN2ALDH1A1 | |
| Acetic Acid SCHEMBL28599804 | 0.74 | LMNA (0.43) | MAPTKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11168519 | 0.73 | KMT2A (0.49) | MAPTSMN1; SMN2ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528455-B1 | Post or preemergence herbicides such as 3-(4-chloro-2-fluoro -5-(1-methoxycarbonyl-1-vinyloxy)phenyl)-1-methyl-6-trifluoro methyl-2,4-pyrimidinedione | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-04 | — | — | US | disclosed |