Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432360 | 0.85 | LMNA (0.47) | LMNAFABP7FABP3FABP5TSHR | |
| SCHEMBL30459416 | 0.85 | LMNA (0.47) | LMNAFABP7FABP3FABP5TSHR | |
| SCHEMBL29897301 | 0.81 | KDM4E (0.50) | LMNAFABP7FABP3FABP5TSHR | |
| SCHEMBL1701383 | 0.81 | KDM4E (0.50) | LMNAFABP7FABP3FABP5TSHR | |
| SCHEMBL9066662 | 0.81 | AKR1B1 (0.38) | LMNATSHRELANEALDH1A1KMT2A | |
| SCHEMBL31192373 | 0.81 | AKR1B1 (0.38) | LMNATSHRELANEALDH1A1KMT2A | |
| SCHEMBL11221300 | 0.79 | CFD (0.42) | ELANEKMT2AATMMEN1RORC | |
| SCHEMBL3785300 | 0.79 | KMT2A (0.53) | LMNATSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL21328044 | 0.79 | KDM4E (0.49) | LMNAFABP7FABP3FABP5TSHR | |
| SCHEMBL21328032 | 0.79 | KDM4E (0.49) | LMNAFABP7FABP3FABP5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034597-A1 | FORCE-RESPONSIVE POLYMERSOMES AND NANOREACTORS; PROCESSES UTILIZING THE SAME | ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) | 2019-02-21 | — | — | WO | claimed |
| WO-2019034597-A1 | FORCE-RESPONSIVE POLYMERSOMES AND NANOREACTORS; PROCESSES UTILIZING THE SAME | ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) | 2019-02-21 | — | — | WO | disclosed |
| US-20080003288-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-7204997-B2 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2007-04-17 | — | — | US | disclosed |
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| US-20030152623-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2003-08-14 | — | — | US | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| US-5976527-A | High surface area support having bound latex particles containing oxirane groups for immobilization of substances | SIOL, WERNER ROEHM GMBH CHEMISHE FABRIK (DE) | 1999-11-02 | — | — | US | disclosed |
| US-4423227-A | SILYLATION, ACYLATION | BOEHRINGER MANNHEIM GMBH (DE) | 1983-12-27 | — | — | US | disclosed |
| EP-0049860-A1 | Process for the preparation of reactive thyroid gland hormones T3 and T4 derivatives that are capable of coupling, and their use | Roche Diagnostics GmbH (DE) | 1982-04-21 | — | — | EP | disclosed |