Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563945 | 0.77 | NPC1 (0.41) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL30949972 | 0.72 | L3MBTL1 (0.49) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL5585308 | 0.72 | KDM4C (0.45) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL1564476 | 0.72 | NPC1 (0.39) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL19127703 | 0.72 | NPC1 (0.51) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL31576127 | 0.72 | KDM4C (0.49) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL25918031 | 0.72 | KDM4C (0.52) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL28796337 | 0.71 | NPC1 (0.50) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL29749639 | 0.71 | NPC1 (0.50) | NPC1RAB9AKDM4CL3MBTL1MEN1 | |
| SCHEMBL2939475 | 0.71 | KDM4C (0.38) | NPC1RAB9AKDM4CL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884093-B | Dopamine D3 ligand compound | 辉瑞公司 | 2021-07-09 | — | — | CN | disclosed |