Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | XDH | P47989 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587007 | 0.85 | NPC1 (0.68) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28589437 | 0.83 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28581423 | 0.82 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28595106 | 0.81 | XDH (0.53) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL22712503 | 0.81 | ALDH1A1 (0.76) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28600151 | 0.80 | KDM4E (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28589454 | 0.80 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL22712499 | 0.78 | ALDH1A1 (0.67) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28574650 | 0.77 | XDH (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL22678610 | 0.77 | ALDH1A1 (0.65) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004208-A | Compound for inhibiting xanthine oxidase activity and preparation method and application thereof | 沈阳药科大学 | 2021-06-22 | — | — | CN | claimed |
| CN-113004208-A | Compound for inhibiting xanthine oxidase activity and preparation method and application thereof | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |