Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 3/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587014 | 0.86 | XDH (0.47) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28586213 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28595108 | 0.82 | XDH (0.44) | KDM4EALDH1A1XDHPTGER1 | |
| SCHEMBL28587011 | 0.82 | XDH (0.45) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28589457 | 0.81 | XDH (0.43) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28600149 | 0.80 | ALDH1A1 (0.76) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28699403 | 0.79 | XDH (0.47) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28574651 | 0.78 | XDH (0.47) | XDHPTGESPTGER1 | |
| SCHEMBL28916533 | 0.77 | XDH (0.53) | XDHPTGER1 | |
| SCHEMBL28589653 | 0.75 | XDH (0.42) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004208-A | Compound for inhibiting xanthine oxidase activity and preparation method and application thereof | 沈阳药科大学 | 2021-06-22 | — | — | CN | claimed |
| CN-113004208-A | Compound for inhibiting xanthine oxidase activity and preparation method and application thereof | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |