Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 4/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832269 | 0.81 | PIK3CA (0.46) | NPC1RAB9AGGPS1PIK3CAMAPT | |
| SCHEMBL2855842 | 0.80 | HTR2C (0.48) | NPC1RAB9AGGPS1PIK3CAHTR2C | |
| SCHEMBL2856614 | 0.77 | PDE5A (0.55) | GGPS1SRCPIK3CAMAPTHTT | |
| SCHEMBL2864782 | 0.75 | MEN1 (0.53) | NPC1RAB9APIK3CAHTR2CABL1 | |
| SCHEMBL2810178 | 0.75 | GAA (0.56) | NPC1RAB9ASRCHTR2CMAPT | |
| SCHEMBL2875609 | 0.74 | HTR2C (0.67) | PIK3CAHTR2CMAPTMEN1KMT2A | |
| SCHEMBL2860019 | 0.73 | PIK3CA (0.58) | GGPS1PIK3CAHTR2CMAPTMEN1 | |
| SCHEMBL2832666 | 0.70 | SRC (0.59) | SRCHTR2CMAPTABL1LMNA | |
| SCHEMBL3185882 | 0.69 | KDM4C (0.47) | GGPS1SRCABCG2 | |
| SCHEMBL2785338 | 0.69 | SRC (0.56) | NPC1RAB9ASRCABL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |