Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 6/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553355 | 0.88 | HTR2C (0.53) | CHRM3HTR2CHTR1ASLC6A2SLC6A4 | |
| SCHEMBL28666071 | 0.78 | CHRM3 (0.48) | CHRM3HTR2CCHRM1CHRM2 | |
| SCHEMBL27561971 | 0.75 | HTR2C (0.51) | CHRM3HTR2CHTR1ASLC6A2SLC6A4 | |
| SCHEMBL83107 | 0.74 | CETP (0.48) | CHRM3HTR2C | |
| Hydrochloric Acid SCHEMBL7669676 | 0.74 | HTR2C (0.53) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2060591 | 0.74 | HSD17B10 (0.43) | CHRM3ALDH1A1 | |
| SCHEMBL5599211 | 0.73 | HSD17B10 (0.51) | ALDH1A1 | |
| SCHEMBL3121349 | 0.73 | HTR2C (0.56) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7676995 | 0.72 | HTR2C (0.53) | CHRM3HTR2CCHRM1CHRM2HTR1A | |
| SCHEMBL4639850 | 0.72 | P2RY14 (0.56) | P2RY14SLC18A3SIGMAR1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121412-A | Preparation method of lefenacin intermediate | 扬州中宝药业股份有限公司 | 2021-07-16 | — | — | CN | disclosed |