Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561971 | 0.84 | HTR2C (0.51) | HTR2CHSD17B10MAP4K1CHRM3CHEK1 | |
| Hydrochloric Acid SCHEMBL7669676 | 0.82 | HTR2C (0.53) | HTR2CHSD17B10MAP4K1CHEK1BRPF1 | |
| SCHEMBL8553355 | 0.82 | HTR2C (0.53) | HTR2CHSD17B10MAP4K1CHRM3CHEK1 | |
| SCHEMBL75151 | 0.81 | CHRM3 (0.43) | CHRM3TLR9TLR8TLR7BRPF1 | |
| SCHEMBL7676995 | 0.81 | HTR2C (0.53) | HTR2CHSD17B10MAP4K1CHRM3CHEK1 | |
| SCHEMBL13556439 | 0.81 | CETP (0.46) | CETPHSD17B10MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL7666631 | 0.80 | HTR2C (0.54) | HTR2CHSD17B10MAP4K1CHRM3CHEK1 | |
| SCHEMBL5660577 | 0.80 | MDM4 (0.50) | CETPHTR2CHSD17B10MAP4K1CHEK1 | |
| Hydrochloric Acid SCHEMBL7672523 | 0.80 | ALDH1A1 (0.53) | HTR2CHSD17B10MAP4K1CHRM3CHEK1 | |
| Hydrochloric Acid SCHEMBL6605507 | 0.79 | HTR2C (0.49) | HTR2CHSD17B10MAP4K1KMT2ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045422-B2 | Piperidine derivatives with pesticidal properties | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-02 | — | — | US | disclosed |
| US-9045422-B2 | Piperidine derivatives with pesticidal properties | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-02 | — | — | US | disclosed |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-21 | — | — | US | disclosed |
| US-8546569-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546569-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120270885-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270885-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090042938-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270885-A1 | CHEMICAL COMPOUNDS | H1-0, CHRM1, MRM1 | CETP 4192/4885HTR2C 3763/4885HSD17B10 4553/4885 |
| US-20090042938-A1 | Chemical Compounds | CHRM1, MRM1, H1-0 | CETP 4119/4885HTR2C 3328/4885HSD17B10 4611/4885 |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | ACHE, CHRM1, CHRM2 | CETP 4092/4885HTR2C 4349/4885HSD17B10 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.